Thesis paper To find out the relationship between renal histopathological changes and differential renal function

Congenital ureteropelvic junction obstruction (UPJO) is by far the most common cause of paediatric hydronephrosis (Allen, TD et al. 1973) with an incidence of about 1 in 1200 live births. Narrowing (persistent obstruction) at this junction reduces the flow of urine from kidney and produces retrograde changes in proximal tract which actually threatens the function of kidney.